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Familial combined hyperlipidemia (FCH) is a genetic disorder that is characterized by high levels of cholesterol and other fats (lipids) in the blood. People with FCH have an increased risk of developing heart disease and stroke, as these conditions are often caused by high levels of cholesterol and other lipids in the blood. The specific cause of FCH is not well understood, but it is thought to be related to an inherited defect in the genes that regulate cholesterol and lipid metabolism.
People with FCH may be at higher risk for developing other conditions, such as type 2 diabetes, as well. Treatment for FCH may include lifestyle changes, such as diet and exercise, and medications to lower cholesterol and other lipids in the blood.