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There is limited scientific research directly comparing the effectiveness of different smart insulin pens. However, there is some evidence to suggest that smart insulin pens can be beneficial for people with diabetes.
For example, a study published in the Journal of Diabetes Science and Technology found that people with type 1 diabetes who used a smart insulin pen for 12 weeks had a significant reduction in their HbA1c levels compared to those who used a traditional insulin pen. The study also found that participants who used the smart insulin pen were more likely to achieve their glycemic targets.
Another study, published in Diabetes Care, found that people with type 2 diabetes who used a smart insulin pen for 6 months had a significant reduction in their time spent in hypoglycemia (low blood sugar) compared to those who used a traditional insulin pen.

While these studies do not directly compare different smart insulin pens, they do provide evidence that smart insulin pens can be helpful for people with diabetes.
In terms of specific features, some smart insulin pens offer features that may be more beneficial for certain people than others. For example, some pens offer the ability to track carbohydrate intake, which can be helpful for people who are trying to lose weight or manage their blood sugar levels more closely.
Other pens offer the ability to share data with loved ones or caregivers, which can be helpful for people who need additional support managing their diabetes.
Ultimately, the best smart insulin pen for a particular person will depend on their individual needs and preferences
InPen Smart Insulin Pen

Overview
The InPen Smart Insulin Pen is a connected insulin pen that helps people with diabetes track their insulin doses and manage their blood sugar levels. The pen connects to a smartphone app via Bluetooth, allowing users to see how much insulin they have taken, when they took it, and how their blood sugar levels are responding.
The InPen is approved by the FDA for use with all types of insulin. It is also compatible with a variety of blood glucose meters, so users can see their insulin doses and blood sugar levels in one place.
Features
- Tracks insulin doses
- Displays blood sugar levels (when used with a compatible blood glucose meter)
- Provides insights into insulin dosing patterns
- Helps identify potential problems with insulin dosing
- Sends reminders for insulin doses
- Shares data with loved ones
Benefits
- Improved glycemic control
- Reduced risk of hypoglycemia
- Increased time in range
- Improved quality of life
- Reduced anxiety about diabetes
- Greater peace of mind for loved ones
Ease of use
The InPen is very easy to use. The pen is simply used to inject insulin as usual. The pen then automatically records the dose of insulin that was taken. The pen can also be used to measure blood sugar levels (when used with a compatible blood glucose meter).
The InPen app is also very easy to use. The app displays a clear and concise overview of insulin doses, blood sugar levels, and other relevant data. The app also provides insights into insulin dosing patterns and can help identify potential problems with insulin dosing.

Cost
The InPen is a more expensive insulin pen than some other options on the market. However, the cost of the InPen may be offset by the benefits of improved glycemic control and reduced risk of complications.
Overall
The InPen Smart Insulin Pen is a valuable tool for people with diabetes who are looking for a way to improve their glycemic control and reduce their risk of complications. The pen is easy to use and provides valuable insights into insulin dosing patterns.
Pros
- Tracks insulin doses
- Displays blood sugar levels (when used with a compatible blood glucose meter)
- Provides insights into insulin dosing patterns
- Helps identify potential problems with insulin dosing
- Sends reminders for insulin doses
- Shares data with loved ones
Cons
- More expensive than some other insulin pens
- Requires a smartphone to use the full range of features
Recommendation
The InPen Smart Insulin Pen is a great option for people with diabetes who are looking for a way to improve their glycemic control and reduce their risk of complications. The pen is easy to use and provides valuable insights into insulin dosing patterns.
NovoPen 6 Smart Insulin Pen

Overview
The NovoPen® 6 is a disposable, pre-filled insulin pen with a built-in dose counter and Bluetooth® connectivity. It is designed to help people with diabetes track their insulin doses and manage their blood sugar levels.
The NovoPen® 6 is approved by the FDA for use with all types of insulin. It is also compatible with a variety of blood glucose meters, so users can see their insulin doses and blood sugar levels in one place.
Features
- Tracks insulin doses
- Displays the last 100 insulin doses
- Connects to the Novo Nordisk Diabetes Management app via Bluetooth®
- Allows users to track their blood sugar levels (when used with a compatible blood glucose meter)
- Provides insights into insulin dosing patterns
- Helps identify potential problems with insulin dosing
- Sends reminders for insulin doses
Benefits
- Improved glycemic control
- Reduced risk of hypoglycemia
- Increased time in range
- Improved quality of life
- Reduced anxiety about diabetes
- Greater peace of mind for loved ones
Ease of use
The NovoPen® 6 is very easy to use. The pen is simply used to inject insulin as usual. The pen then automatically records the dose of insulin that was taken. The pen can also be used to measure blood sugar levels (when used with a compatible blood glucose meter).
The Novo Nordisk Diabetes Management app is also very easy to use. The app displays a clear and concise overview of insulin doses, blood sugar levels, and other relevant data. The app also provides insights into insulin dosing patterns and can help identify potential problems with insulin dosing.

Cost
The NovoPen® 6 is a more expensive insulin pen than some other options on the market. However, the cost of the NovoPen® 6 may be offset by the benefits of improved glycemic control and reduced risk of complications.
Overall
The NovoPen® 6 Smart Insulin Pen is a valuable tool for people with diabetes who are looking for a way to improve their glycemic control and reduce their risk of complications. The pen is easy to use and provides valuable insights into insulin dosing patterns.
Pros
- Tracks insulin doses
- Displays the last 100 insulin doses
- Connects to the Novo Nordisk Diabetes Management app via Bluetooth®
- Allows users to track their blood sugar levels (when used with a compatible blood glucose meter)
- Provides insights into insulin dosing patterns
- Helps identify potential problems with insulin dosing
- Sends reminders for insulin doses
Cons
- More expensive than some other insulin pens
- Requires a smartphone to use the full range of features
Recommendation
The NovoPen® 6 Smart Insulin Pen is a great option for people with diabetes who are looking for a way to improve their glycemic control and reduce their risk of complications. The pen is easy to use and provides valuable insights into insulin dosing patterns.
Huma Smart Pen

Overview
The Huma Smart Pen is a connected insulin pen that helps people with diabetes track their insulin doses and manage their blood sugar levels. The pen connects to a smartphone app via Bluetooth, allowing users to see how much insulin they have taken, when they took it, and how their blood sugar levels are responding.
The Huma Smart Pen is approved by the FDA for use with all types of insulin. It is also compatible with a variety of blood glucose meters, so users can see their insulin doses and blood sugar levels in one place.
Features
- Tracks insulin doses
- Displays blood sugar levels (when used with a compatible blood glucose meter)
- Provides insights into insulin dosing patterns
- Helps identify potential problems with insulin dosing
- Sends reminders for insulin doses
- Shares data with loved ones
- Integrates with Huma’s digital diabetes management platform
Benefits
- Improved glycemic control
- Reduced risk of hypoglycemia
- Increased time in range
- Improved quality of life
- Reduced anxiety about diabetes
- Greater peace of mind for loved ones
Ease of use
The Huma Smart Pen is very easy to use. The pen is simply used to inject insulin as usual. The pen then automatically records the dose of insulin that was taken. The pen can also be used to measure blood sugar levels (when used with a compatible blood glucose meter).
The Huma Smart Pen app is also very easy to use. The app displays a clear and concise overview of insulin doses, blood sugar levels, and other relevant data. The app also provides insights into insulin dosing patterns and can help identify potential problems with insulin dosing.
Cost
The Huma Smart Pen is more expensive than some other insulin pens on the market. However, the cost of the Huma Smart Pen may be offset by the benefits of improved glycemic control and reduced risk of complications.
Overall
The Huma Smart Pen is a valuable tool for people with diabetes who are looking for a way to improve their glycemic control and reduce their risk of complications. The pen is easy to use and provides valuable insights into insulin dosing patterns.
Pros
- Tracks insulin doses
- Displays blood sugar levels (when used with a compatible blood glucose meter)
- Provides insights into insulin dosing patterns
- Helps identify potential problems with insulin dosing
- Sends reminders for insulin doses
- Shares data with loved ones
- Integrates with Huma’s digital diabetes management platform
Cons
- More expensive than some other insulin pens
- Requires a smartphone to use the full range of features
Recommendation
The Huma Smart Pen is a great option for people with diabetes who are looking for a connected insulin pen that can help them improve their glycemic control and reduce their risk of complications. The pen is easy to use and provides valuable insights into insulin dosing patterns.
Selected References
- Heintzman ND. A digital ecosystem of diabetes data and technology: services, systems, and tools enabled by wearables, sensors, and apps. J Diabetes Sci Technol. 2015;10(1):35-41.
- Choudhary P, Campbell F, Joule N, Kar P, Diabetes UK. A type 1 diabetes technology pathway: consensus statement for the use of technology in type 1 diabetes. Diabet Med. 2019;36(5):531-538.
- Fagherazzi G, Ravaud P. Digital diabetes: perspectives for diabetes prevention, management and research. Diabetes Metab Res Rev. 2015;31(6):501-510.