Left Atrial Appendage

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The Left Atrial Appendage (LAA) is a small, pouch-like structure located in the left atrium of the heart. It has gained significant attention in recent years due to its role in cardiac health, particularly in the context of atrial fibrillation (AFib) and stroke prevention.

Left Atrial Appendage (LAA)

Role of the LAA in Atrial Fibrillation and Stroke Risk

Atrial fibrillation is a common heart rhythm disorder where the atria (the upper chambers of the heart) beat irregularly and out of sync with the ventricles. This erratic rhythm can cause blood to pool in the left atrium, particularly within the LAA, where blood clots can form.

Because of its narrow and irregular shape, the LAA is particularly prone to trapping blood, leading to the formation of clots. If a clot forms in the LAA, it can travel through the bloodstream and block an artery in the brain, causing a stroke. In fact, more than 90% of stroke-causing clots in people with AFib originate in the LAA.

Stroke Prevention: LAA Occlusion Devices

For individuals with atrial fibrillation who are at high risk for stroke, but cannot tolerate long-term use of blood-thinning medications (such as warfarin or newer anticoagulants), there are alternative treatment options to reduce stroke risk. One such option is left atrial appendage occlusion, a minimally invasive procedure that involves sealing off the LAA to prevent blood clots from forming there.

Devices such as the WATCHMAN and Amulet are commonly used for LAA occlusion. These devices are inserted via a catheter and placed inside the LAA to close it off from the rest of the atrium. Over time, tissue grows over the device, permanently sealing the LAA. Studies have shown that these devices are effective in reducing stroke risk for AFib patients who are not good candidates for long-term anticoagulation.

Surgical Approaches

In some cases, especially when a patient is already undergoing heart surgery for another reason (such as mitral valve surgery), surgeons may choose to remove or tie off the LAA to reduce the risk of stroke. This procedure can be done via traditional open-heart surgery or through minimally invasive techniques, depending on the patient’s condition and surgical approach.

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